Melatonin (pineal gland hormon, PGH) is a natural hormone produced in the brain – it is pretty powerful antioxidant and, at the same time, it is very important regulator of cancer driving hormones (estrogen, growth factors). Thanks to several scientific discoveries, the anticancer melatonin is becoming an important component in cancer development and cancer prevention.
Human body produces melatonin at a very specific time of the day (exclusively during night darkness) – it is usually produced about 90 minutes after falling asleep in a fully darkened room and it is responsible for deeper sleep.
Melatonin/PGH is produced in the pineal gland. In Eastern medicine the pineal gland was associated with so called “Third Eye” and intuition, and it is linked to an important energy chakra. There is a strong link between pineal gland and human circadian rhythms. Scientists discovered also very specific links between pineal gland and seasonal, sleeping and breeding habits.
Melatonin circadian rhythm
Cancer experts highlight the importance of circadian rhythms not only in cancer development but also in the effectiveness of chemotherapy drugs and the time of day they should be taken. Natural PGH cycle is a part of the circadian system. This is why anticancer melatonin is becoming very important in cancer development and cancer prevention.
Melatonin/PGH production is light sensitive. Several scientific studies demonstrated that irregular sleeping habits and sleeping in light usually reduce the production of PGH – it associated with increased cases of breast cancer. It was also noted that blind women develop less breast cancer.
“Our levels of melatonin are not determined by sleep, as many people think. It is actually the darkness that is important. During the night, if you sleep in a brightly lit room, your PGH levels may be inhibited; however, if you are in the dark but cannot sleep, your melatonin levels will rise normally.”
Prof. Steven M. Hill, Tulane University School of Medicine in New Orleans
Prof. Steven M. Hill and his team note that disruption of circadian rhythms by night shift work or disturbed sleep could result in an increased risk of breast cancer and other diseases.
Melatonin and breast cancer
Hyper production of estrogen is well known as one of important risk factors in breast cancer development. Anticancer melatonin is very important in breast cancer development because PGH regulates excess estrogen levels. It was also noted that night light exposure could make breast cancer tumors resistant to specific anticancer therapy with tamoxifen (in cases of hormone-sensitive tumors).
Melatonin/PGH levels decline with age – increasing the risks of cancer development.
Lack of night sleep is the main reason for reduced production of PGH. It was noted that night shift working men has been shown to triple the rate of prostate cancer, double the rate of bowel cancer, increase the rate of lung cancer by 79% and increase rates of bladder cancer by 70% (Cancer Watch : University of Quebec).
Some experts suggest link between lowered levels of PGH in the bone marrow and leukemia (especially childhood leukemia).
IMPORTANT TO KNOW
Electromagnetic frequencies (WIFI, mobile phones, ETC.) can reduce the production of PGH in human body, allowing estrogen and growth factors levels to increase. Reduced concentration of anticancer melatonin could trigger cancer development.
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