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Top 5 infertility solutions

Infertility is very stressful condition – it is happening when couple cannot conceive after regular unprotected contacts. Frequency of infertility is different in different countries and it vary from 10% to 25% among women of reproductive age (16-44). In general, infertility is identified when couple is not able to achieve pregnancy during 12 months whole having sexual intercourse regularly and without any contraception. Infertility causes can be very different and they can be identified in women, men or both partners. Modern medicine can provide effective successful infertility treatment methods. Here we introduce top 5 infertility solutions.

Top 5 infertility solutions – Hormone therapy (ovulation stimulation)

Women fertility is programmed prior to their birth – healthy females are born with genetically determined egg production. Each healthy woman is able to produce about seven million eggs starting from puberty. According to scientists, healthy woman ovulate approximately 400 times during lifetime (mainly during reproductive period of life). Every month (every menstrual cycle) female body produces several dozen to several hundred of immature eggs but only one or two mature eggs survive up to ovulation. Remaining eggs (small not mature eggs) finish their development by the end of menstrual cycle and reabsorbed by body. After ovulation mature egg moves to Fallopian tube where “meeting” with spermatozoids is happening. Mature egg is absolutely necessary for pregnancy development.

Main cause of several types of infertility is anovulation (absence of ovulation). In these cases most common and most effective is hormone therapy (ovulation stimulation) which can be considered as necessary infertility solution. Ovulation stimulation is recommended in following cases:

  • When women suffer from hormonal dysfunctions and anovulation,
  • When chances of pregnancy can be increased by stimulation of several mature eggs,
  • When assisted reproductive technologies (ART) are needed for infertility treatment – mainly during in-vitro fertilization (IVF).

Hormone therapy can be used only after detailed diagnostic tests. Based on analysis doctor can select certain medication and provide specific treatment schedule.

Most common fertility drugs used for ovulation stimulation include: clomiphene citrate (Seraphene, Clomid), Human Chorionic Gonadotropin (hCG), tamoxifen, HMG: LH/FSH (Letrozole, Repronex, Menopur), human menopausal gonadotropin (hMG), FSH (Follistim/Gonal F, Bravelle), HCG analogs (Profasi or Pregnyl, Ovidrel), Leuprolide (Lupron), Synthetic Gonadotropin (FSH/LH) Inhibitor.

According to health experts, ovulation stimulation often can lead to multiple pregnancies.

Some women could experience unpleasant side effect called “ovarian hyperstimulation syndrome (OHSS)” characterized by significant enlargement of ovaries, possible fluid retention in abdomen and general swelling throughout the body.

Top 5 infertility solutions – Insemination

In most cases of male infertility artificial intrauterine insemination (IUI) can be recommended. Insemination can be done with partner sperm or with donated anonymously sperm. This method of infertility solution can be used also in cases of so called “unexplained infertility” and infertility with cervical factor.

Insemination success rates can be different depending on several factors including age, ovulation status, infertility causes, duration of infertility and quality of sperm.

In most cases insemination can be done during maximum 3-4 menstrual cycles when women have normal ovulation. In cases of polycystic ovarian syndrome (PCOS), endometriosis or hormonal dysfunction the insemination can be used longer up to 6 months.

Before insemination the proper menstrual cycle charting should be done. Sperm should be prepared in special laboratory. Insemination should be carefully schedules – it should be performed during most fertile days (before and during ovulation). According to health experts, sperm can remain viable in female reproductive tract during maximum 5 days and during that period fertilization can occur. At the same time, ovulated egg can be fertilized only during 12-24 hours after ovulation.

Top 5 infertility solutions – In-vitro fertilization

Top 5 infertility solutions

In Vitro Fertilization (IVF) is the most popular method of modern assisted reproductive technologies (ART). It is special technique – process of fertilization by manually combining mature egg and sperm in laboratory dish (artificial fertilization). Next steps include incubator (artificial grow) and following embryo transfer into uterus. Babies conceived after IVF called “test tube babies” or “tube babies”.

IVF is complicated procedure. It includes following steps:

  • Menstrual cycle monitoring, hyperstimulation and monitoring of eggs development;
  • Mature eggs collection;
  • Sperm preparations in special laboratory;
  • Artificial fertilization in laboratory (mixture of mature eggs and active spermatozoid);
  • Embryo development (in special incubators);
  • Embryo transfer into properly prepared uterus.

Top 5 infertility solutions – Surrogacy

Surrogacy can be considered as infertility solution for women without uterus (after hysterectomy) or with uterus physiological problems (immature uterus, fibroids, uterine scars “Asherman syndrome”) and for women who cannot carry pregnancy (health or social reasons). Surrogacy means using one woman’s uterus to implant and carry the embryo and delivers baby for another person or couple. Women who agreed to carry pregnancy called surrogated or surrogate mothers or gestational carriers. In most cases surrogate mother is just a carrier of someone else’s biological child.

Assisted reproductive technologies (ART) are usually used in surrogacy procedures.

Top 5 infertility solutions – ovarian drilling

Ovarian drilling is special surgical technique dedicated to infertility treatment in women with Polycystic Ovary Syndrome (PCOS). Ovarian drilling consists of performing micro-perforations in polycystic ovaries in order to induce ovulation. Nowadays ovarian drilling can be performed during laparoscopy.

According to scientists, about 80% women with PCOS can have babies after ovarian drilling.

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